Ultrasensitive Molecular Detection By Multiphoton Ionization Spectroscopy

J. E. Wessel; D. E. Cooper; C. M. Klimcak

doi:10.1117/12.965814

8 September 1981 Ultrasensitive Molecular Detection By Multiphoton Ionization Spectroscopy

J. E. Wessel, D. E. Cooper, C. M. Klimcak

Proceedings Volume 0286, Laser Spectroscopy for Sensitive Detection; (1981) https://doi.org/10.1117/12.965814
Event: 1981 Technical Symposium East, 1981, Washington, D.C., United States

Abstract

In this paper we describe molecular detection methods based on Multi-Photon Ionization (MPI) spectroscopy that provide high selectivity in addition to excellent detection limits. Prior work based on one-wavelength resonance enhanced 2-photon ionization spectroscopy is reviewed. Highlights include improvement of detection limits for aromatic hydrocarbons by a factor of one-thousand and adaptation of 2-photon ionization for spectrally selective detection in gas chromatography. Two alternative approaches for highly selective MPI detec-tion are discussed. Time-of-Flight (TOF) ion analysis in conjunction with MPI provides mass spectral signatures in addition to MPI spectra. Single ion sensitivity can be approached in this configuration. In a purely optical approach, selectivity can be improved by using two-color excitation. The new two-color method of Ion Dip Spectroscopy (IDS) can be used to label specific intermediate states involved in the MPI process and it is capable of generating Raman-type spectra as a supplement to the MPI spectra. The ultimate detection limit of the IDS method is expected to be about 104 molecules/ cm3, which is comparable to the detection limit that we have obtained for naphthalene by one-color MPI.

Citation Download Citation

J. E. Wessel, D. E. Cooper, and C. M. Klimcak "Ultrasensitive Molecular Detection By Multiphoton Ionization Spectroscopy", Proc. SPIE 0286, Laser Spectroscopy for Sensitive Detection, (8 September 1981); https://doi.org/10.1117/12.965814

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