Novel Fluorescent Label For Time-Resolved Fluorescence Immunoassay

Richard B Thompson; Lydia M Vallarino

doi:10.1117/12.945423

24 June 1988 Novel Fluorescent Label For Time-Resolved Fluorescence Immunoassay

Richard B Thompson, Lydia M Vallarino

Proceedings Volume 0909, Time-Resolved Laser Spectroscopy in Biochemistry; (1988) https://doi.org/10.1117/12.945423
Event: 1988 Los Angeles Symposium: O-E/LASE '88, 1988, Los Angeles, CA, United States

Abstract

Several workers have recently shown that time-resolved methods (or their frequency domain analogs) can offer significant improvements in the sensitivity of fluorescence immunoassays. However, the fluorescent labels most often used, chelates of terbium and europium have some drawbacks. We have developed a new fluorescent label with improved characteristics for such immunoassays, including excitation in the visible by laser sources, no requirement for a separate "enhancer solution", good time resolution characteristics, and the capability to be passively concentrated out of solution in front of the detector optics.

Citation Download Citation

Richard B Thompson and Lydia M Vallarino "Novel Fluorescent Label For Time-Resolved Fluorescence Immunoassay", Proc. SPIE 0909, Time-Resolved Laser Spectroscopy in Biochemistry, (24 June 1988); https://doi.org/10.1117/12.945423

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