Contrast improvement for swept source optical coherence tomography image of sub-surface tissue

Xinyu Li; Shanshan Liang; Jun Zhang

doi:10.1117/12.2251650

20 February 2017 Contrast improvement for swept source optical coherence tomography image of sub-surface tissue

Xinyu Li, Shanshan Liang, Jun Zhang

Proceedings Volume 10053, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXI; 100532R (2017) https://doi.org/10.1117/12.2251650
Event: SPIE BiOS, 2017, San Francisco, California, United States

Abstract

Swept source optical coherence tomography (SSOCT) is an attractive biological imaging technology due to its advantages of simple setup and high imaging speed. As the light intensity attenuated rapidly in high scattering biological tissues, the contrast of OCT image will drop with depth. In this paper a new method was introduced to compensate the attenuation of imaging contrast in SSOCT. The interference signal was divided into two channels of analog to digital converter (ADC) with a splitting ratio of 1:5. The higher level signal in one channel was used to reconstruct deeper structure of tissue and the lower level signal in the other channel was used to reconstruct surface structure of tissue. Lowfrequency signals in one channel were filtered by a high pass filter and then combined with the signal in the other channel to obtain a high contrast image in both surface and deep area of tissue. Human finger and porcine airway imaging obtained with the system show that the contrast of SSOCT images can be improved in deeper region of tissue.

Citation Download Citation

Xinyu Li, Shanshan Liang, and Jun Zhang "Contrast improvement for swept source optical coherence tomography image of sub-surface tissue", Proc. SPIE 10053, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXI, 100532R (20 February 2017); https://doi.org/10.1117/12.2251650

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