Poster + Presentation + Paper
5 March 2021 Integrated amplifier with complementary organic electrochemical transistors for high-sensitivity ion detection and real-time monitoring
Author Affiliations +
Conference Poster
Abstract
Ions are fundamental biological regulators enabling the communication between cells, regulating metabolic and bioenergetic processing and playing a key role in pH regulation and hydration. The in-situ quantification of the ion concentration is gathering relevant interest in biomedical diagnostics and healthcare. State-of-art transistor-based ion sensors show an intrinsic trade-off between sensitivity, operating range and supply voltage. To overcome these limitations, here we focus on ion sensor amplifiers where complementary OECTs are integrated in a push-pull configuration, providing sensitivity larger than 1 V/dec at a supply voltage down to 0.5 V and operating in the physiological range. Ion detection over a range of five orders of magnitude and real-time monitoring of variations two orders of magnitude lower than the detected concentration are achieved. The ion-sensitive amplifier sets a new benchmark for ion-sensing devices, opening possibilities for predictive diagnostics and personalized medicine.
Conference Presentation
© (2021) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Fabrizio Torricelli, Paolo Romele, Paschalis Gkoupidenis, Dimitrios A. Koutsouras, Katharina Lieberth, Zsolt M. Kovács-Vajna, and Paul W. M. Blom "Integrated amplifier with complementary organic electrochemical transistors for high-sensitivity ion detection and real-time monitoring", Proc. SPIE 11663, Integrated Sensors for Biological and Neural Sensing, 1166314 (5 March 2021); https://doi.org/10.1117/12.2583428
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KEYWORDS
Ions

Amplifiers

Transistors

Sensors

Blood

Diagnostics

Failure analysis

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