Dual-comb biosensing of SARS-CoV-2 nucleocapsid protein antigen

Shogo Miyamura; Ryo Oe; Takuya Nakahara; Shuji Taue; Yu Tokizane; Takeo Minamikawa; Taira Kajisa; Takeshi Yasui

doi:10.1117/12.2651247

6 March 2023 Dual-comb biosensing of SARS-CoV-2 nucleocapsid protein antigen

Shogo Miyamura, Ryo Oe, Takuya Nakahara, Shuji Taue, Yu Tokizane, Takeo Minamikawa, Taira Kajisa, Takeshi Yasui

Proceedings Volume 12372, Optical Fibers and Sensors for Medical Diagnostics, Treatment and Environmental Applications XXIII; 1237207 (2023) https://doi.org/10.1117/12.2651247
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

One interesting feature of optical frequency comb (OFC) is a function of frequency conversion between region and electric regions. While such feature has been used for generation of correct electric signal in microwave or millimeter region, it can be further used for fiber biosensing; namely, biosensing OFC. In this paper, we demonstrated detection of SARS-CoV-2 antigen based on a combination of dual fiber combs, an intracavity multi-mode-interference fiber sensor, and sensor surface modification of SARS-CoV-2 antibody.

Conference Presentation

Citation Download Citation

Shogo Miyamura, Ryo Oe, Takuya Nakahara, Shuji Taue, Yu Tokizane, Takeo Minamikawa, Taira Kajisa, and Takeshi Yasui "Dual-comb biosensing of SARS-CoV-2 nucleocapsid protein antigen", Proc. SPIE 12372, Optical Fibers and Sensors for Medical Diagnostics, Treatment and Environmental Applications XXIII, 1237207 (6 March 2023); https://doi.org/10.1117/12.2651247

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available