Spectral and photochemical parameters which define the higher efficacy of laser phototherapy in hyperbilirubinemia in newborns

Vasili A. Mostovnikov; Galina R. Mostovnikova; Vitali Yu Plavski

doi:10.1117/12.197489

2 January 1995 Spectral and photochemical parameters which define the higher efficacy of laser phototherapy in hyperbilirubinemia in newborns

Vasili A. Mostovnikov, Galina R. Mostovnikova, Vitali Yu Plavski

Author Affiliations +

Proceedings Volume 2370, 5th International Conference on Laser Applications in Life Sciences; (1995) https://doi.org/10.1117/12.197489
Event: Laser Applications in Life Sciences: 5th International Conference, 1994, Minsk, Belarus

Abstract

It is shown that the efficacy of phototherapy of neonatal hyperbilirubinemia is considerably increased with substitution of traditional lamp sources by the argon laser light. The spectral range of the laser (476.5 - 514.5 nm) corresponds to low-frequency slope of bilirubin absorption spectrum. This rises quantum yield of lumirubin formation which is known for its high rate of excretion. The fact can be explained by the form of absorption spectrum of bilirubin which is the sum of two spectra of weakly bound chromophores, the spectrum of chromophore responsible for lumirubin production being shifted to lower frequencies. The second cause of higher efficacy of laser phototherapy with wavelength span 476.5 ... 514.5 is the less shielding effect of hemoglobin.

Citation Download Citation

Vasili A. Mostovnikov, Galina R. Mostovnikova, and Vitali Yu Plavski "Spectral and photochemical parameters which define the higher efficacy of laser phototherapy in hyperbilirubinemia in newborns", Proc. SPIE 2370, 5th International Conference on Laser Applications in Life Sciences, (2 January 1995); https://doi.org/10.1117/12.197489

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available