Interferometric testing of the random phase objects (biological tissue models) by spatially-modulated laser beam

Vladimir P. Ryabukho; Anatoly A. Chaussky; Vladimir L. Khomutov; Valery V. Tuchin; Irina F. Terent'eva

doi:10.1117/12.231689

9 February 1996 Interferometric testing of the random phase objects (biological tissue models) by spatially modulated laser beam

Vladimir P. Ryabukho, Anatoly A. Chaussky, Vladimir L. Khomutov, Valery V. Tuchin, Irina F. Terent'eva

Author Affiliations +

Proceedings Volume 2732, CIS Selected Papers: Coherence-Domain Methods in Biomedical Optics; (1996) https://doi.org/10.1117/12.231689
Event: CIS Selected Papers: Coherence Domain Methods in Biomedical Optics, 1995, Saratov, Russian Federation

Abstract

The diffraction of a laser beam with a spatial amplitude-phase modulation in the form of regular interference pattern behind random phase object as biological tissue model is studied. The interference effects of speckle-fields formed in diffraction zone are considered. The concept of interference of mutually shifted partially developed identical speckle fields has been employed. The evolution of visibility of average intensity fringes formed in scattered field has been studied for the objects with different statistical parameters modeling various cell structures including objects with an oscillating correlation coefficient of phase inhomogeneities. The behavior of the speckle field interference induced by the focused spatially-modulated laser beam diffraction on the random phase objects has been studied. A new measuring technique of statistical parameters of transparent or reflecting random phase objects is discussed. The technique is based on the usage of the probing beam with regular interference pattern, focused on a moving object, and on measurement of contrast of average intensity fringes, formed in scattering dynamic speckle-modulated field. Biomedical applications of the developed modeling and measuring technique are discussed.

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Vladimir P. Ryabukho, Anatoly A. Chaussky, Vladimir L. Khomutov, Valery V. Tuchin, and Irina F. Terent'eva "Interferometric testing of the random phase objects (biological tissue models) by spatially modulated laser beam", Proc. SPIE 2732, CIS Selected Papers: Coherence-Domain Methods in Biomedical Optics, (9 February 1996); https://doi.org/10.1117/12.231689

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