Lifetimes of normal and tumorous human lung tissues by time-resolved fluorescence spectra

Wei Zheng; Zhiwei Huang; Shusen Xie; Teck-Chee Chia; Zukang Lu; Jin Kai Chen

doi:10.1117/12.251945

23 September 1996 Lifetimes of normal and tumorous human lung tissues by time-resolved fluorescence spectra

Wei Zheng, Zhiwei Huang, Shusen Xie, Teck-Chee Chia, Zukang Lu, Jin Kai Chen

Proceedings Volume 2887, Lasers in Medicine and Dentistry: Diagnostics and Treatment; (1996) https://doi.org/10.1117/12.251945
Event: Photonics China '96, 1996, Beijing, China

Abstract

The steady fluorescence spectra and fluorescence decay profiles from cancerous human lung tissues in vitro are measured using time-resolved technique. The fluorescence decays could be obtained by least-square fitting based on monoexponential function, with fluorescence lifetime constants of 6.3, 5.6 and 5.1 ns, respectively, corresponding to the normal, squamous carcinoma and adenocarcinoma tissues. The results show that they decay time of tumor tissue is a bit fast compared to the normal tissue.

Citation Download Citation

Wei Zheng, Zhiwei Huang, Shusen Xie, Teck-Chee Chia, Zukang Lu, and Jin Kai Chen "Lifetimes of normal and tumorous human lung tissues by time-resolved fluorescence spectra", Proc. SPIE 2887, Lasers in Medicine and Dentistry: Diagnostics and Treatment, (23 September 1996); https://doi.org/10.1117/12.251945

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