Gel-immobilized molecular beacons for label-free DNA hybridization detection

Hong Wang; Jiong Li; Quanjun Liu; Heping Liu; Zuhong Lu

doi:10.1117/12.440235

14 September 2001 Gel-immobilized molecular beacons for label-free DNA hybridization detection

Hong Wang, Jiong Li, Quanjun Liu, Heping Liu, Zuhong Lu

Proceedings Volume 4414, International Conference on Sensor Technology (ISTC 2001); (2001) https://doi.org/10.1117/12.440235
Event: International Conference on Sensing units and Sensor Technology, 2001, Wuhan, China

Abstract

We report gel-immobilized molecular beacon for DNA hybridization detection in this paper. The specially designed molecular beacons were covalently immobilized in polyacrylamide gel pads array. After hybridization, the complementary noncomplementary target can be easily distinguished with gel-immobilized molecular beacon probes. The results indicate the potential applications of this new gel-immobilized molecular beacon array in parallel, cost effective and label-free DNA hybridization detection.

Citation Download Citation

Hong Wang, Jiong Li, Quanjun Liu, Heping Liu, and Zuhong Lu "Gel-immobilized molecular beacons for label-free DNA hybridization detection", Proc. SPIE 4414, International Conference on Sensor Technology (ISTC 2001), (14 September 2001); https://doi.org/10.1117/12.440235

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