Skin optical clearing for improvement of laser tattoo removal

Elina A. Genina; Alexey N. Bashkatov; Anna A. Gavrilova; Alexander B. Pravdin; Valery V. Tuchin; Ilya V. Yaroslavsky; Gregory B. Altshuler

doi:10.1117/12.753224

1 August 2007 Skin optical clearing for improvement of laser tattoo removal

Elina A. Genina, Alexey N. Bashkatov, Anna A. Gavrilova, Alexander B. Pravdin, Valery V. Tuchin, Ilya V. Yaroslavsky, Gregory B. Altshuler

Author Affiliations +

Proceedings Volume 6734, International Conference on Lasers, Applications, and Technologies 2007: Laser Technologies for Medicine; 673419 (2007) https://doi.org/10.1117/12.753224
Event: International Conference on Lasers, Applications, and Technologies '07, 2007, Minsk, Belarus

Abstract

The removal of tattoo pigments by laser energy is effected through a process of selective photothermolysis. Dehydration and optical immersion based on refractive index matching of scattering centers with that of surrounding matter through introduction of an exogenous index-matching agent can improve laser tattoo removal by providing increased efficiency of laser delivery to embedded ink particles and enabling the use of shorter wavelength visible lasers more effective on certain inks. Effectiveness of a method of accelerating penetration of the index-matching compounds by enhancing skin permeability through creating a lattice of micro-zones of limited thermal damage in the stratum corneum was studied. As optical clearing agents 100% and 88%-aqueous glycerol solutions were used. The effect of stratum corneum perforation on the rate of the immersion clearing of skin was studied. Dynamics of refractive index alteration of glycerol solution during its interaction with skin samples was monitored. Improvement of tattoo visualization was observed. The results of the experiments have shown that the lattice of island damage method the is effective for transepidermal delivery of optical clearing agents and could be used successfully in in vivo conditions for the enhancement of optical clearing of treated skin area and as enabling improvement of laser tattoo removal.

Citation Download Citation

Elina A. Genina, Alexey N. Bashkatov, Anna A. Gavrilova, Alexander B. Pravdin, Valery V. Tuchin, Ilya V. Yaroslavsky, and Gregory B. Altshuler "Skin optical clearing for improvement of laser tattoo removal", Proc. SPIE 6734, International Conference on Lasers, Applications, and Technologies 2007: Laser Technologies for Medicine, 673419 (1 August 2007); https://doi.org/10.1117/12.753224

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
9 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Skin

Refractive index

Laser induced damage

Optical clearing

Water

Laser scattering

Tissue optics

Show All Keywords

Keywords/Phrases

Search In:

Publication Years