Paper
13 July 2009 Photodynamic dosimetry in the treatment of periodontitis
Author Affiliations +
Proceedings Volume 7380, Photodynamic Therapy: Back to the Future; 73803E (2009) https://doi.org/10.1117/12.822941
Event: 12th World Congress of the International Photodynamic Association, 2009, Seattle, Washington, United States
Abstract
Photodynamic therapy has been demonstrated to effectively kill human periopathogens in vitro. However, the translation of in vitro work to in vivo clinical efficacy has been difficult due to the number of variables present in any given patient. Parameters such as photosensitizer concentration, duration of light therapy and amount of light delivered to the target tissue all play a role in the dose response of PDT in vivo. In this 121 patient study we kept all parameters the same except for light dose which was delivered at either 150 mW or 220 mW. This clearly demonstrated the clinical benefits of a higher light dose in the treatment of periodontitis.
© (2009) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Roger C. Andersen, Nicolas G. Loebel, and Dane M. Andersen "Photodynamic dosimetry in the treatment of periodontitis", Proc. SPIE 7380, Photodynamic Therapy: Back to the Future, 73803E (13 July 2009); https://doi.org/10.1117/12.822941
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KEYWORDS
Photodynamic therapy

Tissues

Teeth

Mouth

Oxygen

Statistical analysis

Therapeutics

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