A real-time measurement system for parameters of live biology metabolism process with fiber optics

Wei Tao; Hui Zhao; Zemin Liu; Jinke Cheng; Rong Cai

doi:10.1117/12.886217

31 December 2010 A real-time measurement system for parameters of live biology metabolism process with fiber optics

Wei Tao, Hui Zhao, Zemin Liu, Jinke Cheng, Rong Cai

Proceedings Volume 7544, Sixth International Symposium on Precision Engineering Measurements and Instrumentation; 75444U (2010) https://doi.org/10.1117/12.886217
Event: Sixth International Symposium on Precision Engineering Measurements and Instrumentation, 2010, Hangzhou, China

Abstract

Energy metabolism is one of the basic life activities of cellular in which lactate, O₂ and CO₂ will be released into the extracellular environment. By monitoring the quantity of these parameters, the mitochondrial performance will be got. A continuous measurement system for the concentration of O₂, CO₂ and PH value is introduced in this paper. The system is made up of several small-sized fiber optics biosensors corresponding to the container. The setup of the system and the principle of measurement of several parameters are explained. The setup of the fiber PH sensor based on principle of light absorption is also introduced in detail and some experimental results are given. From the results we can see that the system can measure the PH value precisely suitable for cell cultivation. The linear and repeatable accuracies are 3.6% and 6.7% respectively, which can fulfill the measurement task.

Citation Download Citation

Wei Tao, Hui Zhao, Zemin Liu, Jinke Cheng, and Rong Cai "A real-time measurement system for parameters of live biology metabolism process with fiber optics", Proc. SPIE 7544, Sixth International Symposium on Precision Engineering Measurements and Instrumentation, 75444U (31 December 2010); https://doi.org/10.1117/12.886217

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