Cancer diagnostics using spatially resolved fluorescence-based optical imaging

Daniela Strat; André Liemert; Wolfgang S. L. Strauss; Alwin Kienle

doi:10.1117/12.841711

22 February 2010 Cancer diagnostics using spatially resolved fluorescence-based optical imaging

Daniela Strat, André Liemert, Wolfgang S. L. Strauss, Alwin Kienle

Proceedings Volume 7555, Advanced Biomedical and Clinical Diagnostic Systems VIII; 75550J (2010) https://doi.org/10.1117/12.841711
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

We propose a cancer diagnostics method using 3D reconstruction of fluorescence based optical imaging data. The reconstruction of luminescence sources in biological tissue is investigated using data obtained from Monte Carlo simulations as well as simulated data using the diffusion approximation. The absolute determination of the tumor locations is dependent on the information gathered by the recorded data. To tackle the forward problem we used the solution of the diffusion equation for a cube. The inverse problem is solved.

Citation Download Citation

Daniela Strat, André Liemert, Wolfgang S. L. Strauss, and Alwin Kienle "Cancer diagnostics using spatially resolved fluorescence-based optical imaging", Proc. SPIE 7555, Advanced Biomedical and Clinical Diagnostic Systems VIII, 75550J (22 February 2010); https://doi.org/10.1117/12.841711

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