Ultrashort IR Laser Pulse Isomerization Of All-Trans Retinal To 11 CIS Retinal

J. Taboada; J. Liegner; A. T.C. Tsin

doi:10.1117/12.967132

1 January 1987 Ultrashort IR Laser Pulse Isomerization Of All-Trans Retinal To 11 CIS Retinal

J. Taboada, J. Liegner, A. T.C. Tsin

Proceedings Volume 0813, Optics and the Information Age; (1987) https://doi.org/10.1117/12.967132
Event: 14th Congress of the International Commission for Optics, 1987, Quebec, Canada

Abstract

The mammalian ocular system possesses a significant IR transmission window between the longest visually detectable light wavelength at 700 nm and the cut off water absorption band at 1400 nm. This near IR optical band may provide a channel for controlling vision processes. Of particular interest is the regeneration process which involves the re -Wmerization of all-trans retinal to 11-cis retinal and the molecular recoupling of retinal with opsin.". This re-isomerization, moving against potential energy gradient, is the rate limiting step is assumed to involve either a vitamin A intermediate or a directly applied enzyme, "isomerase"). The concept investigated in this study concerns the possibility of directly influencing the isomerization process by ultrashort IR laser pulses.

Citation Download Citation

J. Taboada, J. Liegner, and A. T.C. Tsin "Ultrashort IR Laser Pulse Isomerization Of All-Trans Retinal To 11 CIS Retinal", Proc. SPIE 0813, Optics and the Information Age, (1 January 1987); https://doi.org/10.1117/12.967132

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