Image enhancement of optical images for binary system of melanocytes and keratinocytes

S. Takanezawa; A. Baba; Y. Sako; Y. Ozaki; A. Date; K. Toyama; S. Morita

doi:10.1117/12.2018681

20 May 2013 Image enhancement of optical images for binary system of melanocytes and keratinocytes

S. Takanezawa, A. Baba, Y. Sako, Y. Ozaki, A. Date, K. Toyama, S. Morita

Proceedings Volume 8879, Nano-Bio Sensing, Imaging, and Spectroscopy; 88790I (2013) https://doi.org/10.1117/12.2018681
Event: Nano-Bio Sensing, Imaging and Spectroscopy, 2013, Jeju, Korea, Republic of

Abstract

Automatic determination of the cell shapes of large numbers of melanocytes based on optical images of human skin models have been largely unsuccessful (the complexities introduced by dendrites and the melanin pigmentation over the keratinocytes to give unclear outlines). Here, we present an image enhancement procedure for enhancing the contrast of images with removing the non-uniformity of background. The brightness is normalized also for the non-uniform population density of melanocytes.

Citation Download Citation

S. Takanezawa, A. Baba, Y. Sako, Y. Ozaki, A. Date, K. Toyama, and S. Morita "Image enhancement of optical images for binary system of melanocytes and keratinocytes", Proc. SPIE 8879, Nano-Bio Sensing, Imaging, and Spectroscopy, 88790I (20 May 2013); https://doi.org/10.1117/12.2018681

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