Improved in vivo imaging of human blood circulation in the chorioretinal complex using phase variance method with
new phase stabilized 1 μm swept-source optical coherence tomography (pv-SSOCT)

Raju Poddar; Dae Yu Kim; John S. Werner; Robert J. Zawadzki

doi:10.1117/12.2040186

28 February 2014 Improved in vivo imaging of human blood circulation in the chorioretinal complex using phase variance method with new phase stabilized 1 μm swept-source optical coherence tomography (pv-SSOCT)

Raju Poddar, Dae Yu Kim, John S. Werner, Robert J. Zawadzki

Author Affiliations +

Proceedings Volume 8930, Ophthalmic Technologies XXIV; 89300X (2014) https://doi.org/10.1117/12.2040186
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

We demonstrate the feasibility of our newly developed phase stabilized high-speed (100 kHz A-scans/s) 1 μm sweptsource optical coherence tomography (SSOCT) system with the phase-variance based motion contrast method for visualization of human chorioretinal complex microcirculation. Compared to our previously reported spectral domain (spectrometer based) phase-variance (pv)-SDOCT system it has advantages of higher sensitivity, reduced fringe washout for high blood flow speeds and deeper penetration in choroid. High phase stability SSOCT imaging was achieved by using a computationally efficient phase stabilization approach. This process does not require additional calibration hardware and complex numerical procedures. Our phase stabilization method is simple and can be employed in a variety of SS-OCT systems. Examples of vasculature in the chorioretinal complex imaged by pv-SSOCT is presented and compared to retinal images of the same volunteers acquired with fluorescein angiography (FA) and indocyanine green angiography (ICGA).

Citation Download Citation

Raju Poddar, Dae Yu Kim, John S. Werner, and Robert J. Zawadzki "Improved in vivo imaging of human blood circulation in the chorioretinal complex using phase variance method with new phase stabilized 1 μm swept-source optical coherence tomography (pv-SSOCT)", Proc. SPIE 8930, Ophthalmic Technologies XXIV, 89300X (28 February 2014); https://doi.org/10.1117/12.2040186

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available