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The distribution and morphology of cortical actin filaments are essential in cell dynamics, such as cell division. In this work, we propose a plasmonic approach for long term imaging to study the specifications of actin dynamics in live cells. Here, we employ a new imaging setup which can acquire a set of images with spatial sparsity. Long-term and super-resolution imaging can be achieved by our imaging setup. We demonstrate examples of different morphologies of cortical actin filaments during cell division.
Guangjie Cui,Zhijia Zhang,Xintao Zhao, andSomin Eunice Lee
"Super-resolution plasmonic imaging & angular analysis of actin", Proc. SPIE PC11978, Plasmonics in Biology and Medicine XIX, PC1197803 (3 March 2022); https://doi.org/10.1117/12.2610160
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