Pilot study on optical hydration status measurement using short wavelength infrared spectroscopy (Conference Presentation)

June-Young Lee; Jeongyun Seo; Woochang Lee; Sung Hyun Nam

doi:10.1117/12.2646467

16 March 2023 Pilot study on optical hydration status measurement using short wavelength infrared spectroscopy (Conference Presentation)

June-Young Lee, Jeongyun Seo, Woochang Lee, Sung Hyun Nam

Author Affiliations +

Proceedings Volume PC12387, Optical Diagnostics and Sensing XXIII: Toward Point-of-Care Diagnostics; PC1238703 (2023) https://doi.org/10.1117/12.2646467
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

We suggest a method to monitor dehydration status using the change of albumin concentration measured from short wavelength infrared (SWIR) in-vivo spectrum. Absorption spectra were measured on swine skin using Fourier transform infrared spectroscopy based system, while dehydration and rehydration of the swine subject were induced by intravenous infusion of mannitol and saline solutions, respectively. The effective water path length and the amount of albumin absorption were regressed from the measured skin spectrum. Then, albumin concentration was acquired by normalizing albumin absorption by water path length. Experimental results showed that albumin concentration increases during dehydration period and decreases during rehydration period, which indicates the possibility of SWIR spectroscopy as a means for optical hydration status monitoring.

Conference Presentation

Citation Download Citation

June-Young Lee, Jeongyun Seo, Woochang Lee, and Sung Hyun Nam "Pilot study on optical hydration status measurement using short wavelength infrared spectroscopy (Conference Presentation)", Proc. SPIE PC12387, Optical Diagnostics and Sensing XXIII: Toward Point-of-Care Diagnostics, PC1238703 (16 March 2023); https://doi.org/10.1117/12.2646467

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KEYWORDS

Infrared spectroscopy

Optical testing

Short wave infrared radiation

Absorption

Skin

Blood

In vivo imaging

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