Measurement of optical path length change following pulsed laser irradiation using differential phase optical coherence tomography

Kim, Jihoon; Oh, Junghwan; Milner, Thomas E.

doi:doi:10.1117/1.2236289

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Journal of Biomedical Optics / Volume 11 / Issue 4 / Special Section on Pioneers in Biomedical Optics: A.J. Welch

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Measurement of optical path length change following pulsed laser irradiation using differential phase optical coherence tomography

J. Biomed. Opt. 11, 041122 (Jul 24, 2006); http://dx.doi.org/10.1117/1.2236289

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Abstract

References (23)

Citing Articles (3)

Jihoon Kim, Junghwan Oh, and Thomas E. Milner

The University of Texas at Austin, Department of Biomedical Engineering, 1 University Station, C0800, Austin, Texas 78712

Differential phase optical coherence tomography (DPOCT) is introduced to measure optical path length changes in response to pulsed laser irradiation (585 nm). An analytical equation that includes thermoelastic surface displacement and thermorefractive index change is derived to predict optical path length change in response to pulsed laser irradiation for both “confined surface” and “free surface” model systems. The derived equation is tested by comparing predicted values with data recorded from experiments using two model systems. Thermorefractive index change and the thermal expansion coefficient are deduced from differential phase change (dΔϕ) and temperature increase (ΔT₀) measurements. The measured n(T₀)β(T₀)+dn/dT[ = 1.74⋅10⁻⁴±1.7⋅10⁻⁶ (1/K)] in the free surface experiment matches with the National Institute of Standards and Technology (NIST) data value [ = 1.77⋅10⁻⁴ (1/K)]. Exclusion of lateral thermal expansion in the analytical model for the confined surface experiment causes difference between the measured dn/dT[ = −2.3⋅10⁻⁴±7.3⋅10⁻⁶(1/K)] and the NIST value [ = −9.45⋅10⁻⁵ (1/K)]. In spite of the difference in the confined surface experiment, results of our studies indicate DPOCT can detect dynamic optical path length change in response to pulsed laser irradiation with high sensitivity, and applications to tissue diagnostics may be possible.

History

Received Sep 30, 2005
Accepted Feb 02, 2006
Revised Feb 02, 2006
Published online Jul 24, 2006

Digital Object Identifier

http://dx.doi.org/10.1117/1.2236289

Citation

Jihoon Kim, Junghwan Oh and Thomas E. Milner, "Measurement of optical path length change following pulsed laser irradiation using differential phase optical coherence tomography", J. Biomed. Opt. 11, 041122 (Jul 24, 2006); http://dx.doi.org/10.1117/1.2236289