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Emerging concepts of laser-activated nanoparticles for tissue bonding
J. Biomed. Opt. 17, 010701 (Jan 19, 2012); http://dx.doi.org/10.1117/1.JBO.17.1.010701
We report recent achievements and future perspectives of minimally invasive bonding of biological tissues triggered by laser light. In particular, we review new advancements in the biomedical exploitation of near-infrared absorbing gold nanoparticles as an original solution for the photothermal closure of surgical incisions. Advanced concepts of laser tissue bonding involving the application of hybrid nanocomposites obtained by inclusion of nanochromophores into biopolymer scaffolds are also introduced. The perspectives of tissue bonding are discussed in the following aspects: (1) tissue bonding with highly-stabilized nanochromophores, (2) enhanced tissue bonding with patterned nanocomposites, (3) real-time monitoring of temperature distributions, (4) tracking of tissue regeneration based on the optical resonances of gold nanoparticles.
© 2012 Society of Photo-Optical Instrumentation Engineers
History
Received Aug 08, 2011
Revised Oct 25, 2011
Published online Jan 19, 2012
Revised Oct 25, 2011
Published online Jan 19, 2012
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Paolo Matteini, Fulvio Ratto, Francesca Rossi and Roberto Pini, "Emerging concepts of laser-activated nanoparticles for tissue bonding",
J. Biomed. Opt. 17, 010701 (Jan 19, 2012); http://dx.doi.org/10.1117/1.JBO.17.1.010701
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