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Correlation of visually evoked intrinsic optical signals and electroretinograms recorded from chicken retina with a combined functional optical coherence tomography and electroretinography system
J. Biomed. Opt. 17, 016011 (Feb 08, 2012); http://dx.doi.org/10.1117/1.JBO.17.1.016011
Visually evoked fast intrinsic optical signals (IOSs) were recorded for the first time in vivo from all layers of healthy chicken retina by using a combined functional optical coherence tomography (fOCT) and electroretinography (ERG) system. The fast IOSs were observed to develop within ∼ 5 ms from the on-set of the visual stimulus, whereas slow IOSs were measured up to 1 s later. The visually evoked IOSs and ERG traces were recorded simultaneously, and a clear correlation was observed between them. The ability to measure visually evoked fast IOSs non-invasively and in vivo from individual retinal layers could significantly improve the understanding of the complex communication between different retinal cell types in healthy and diseased retinas.
© 2012 Society of Photo-Optical Instrumentation Engineers
History
Received Aug 16, 2011
Accepted Nov 17, 2011
Revised Nov 16, 2011
Published online Feb 08, 2012
Accepted Nov 17, 2011
Revised Nov 16, 2011
Published online Feb 08, 2012
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Alireza Akhlagh Moayed, Sepideh Hariri, Vivian Choh and Kostadinka Bizheva, "Correlation of visually evoked intrinsic optical signals and electroretinograms recorded from chicken retina with a combined functional optical coherence tomography and electroretinography system",
J. Biomed. Opt. 17, 016011 (Feb 08, 2012); http://dx.doi.org/10.1117/1.JBO.17.1.016011
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