Multifunctional nanoprobe to enhance the utility of optical based imaging techniques

Jung, Yeongri; Guan, Guangying; Wei, Chen-wei; Reif, Roberto; Gao, Xiaohu; O’Donnell, Matthew; Wang, Ruikang K.

doi:doi:10.1117/1.JBO.17.1.016015

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Journal of Biomedical Optics / Volume 17 / Issue 1 / Research Papers: Imaging

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Multifunctional nanoprobe to enhance the utility of optical based imaging techniques

J. Biomed. Opt. 17, 016015 (Jan 31, 2012); http://dx.doi.org/10.1117/1.JBO.17.1.016015

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Abstract

References (17)

Yeongri Jung, Guangying Guan, Chen-wei Wei, Roberto Reif, Xiaohu Gao, Matthew O’Donnell, and Ruikang K. Wang

University of Washington, Department of Bioengineering, 3720 15th Avenue NE, Seattle, Washington 98195

Several imaging modalities such as optical coherence tomography, photothermal, photoacoustic and magnetic resonance imaging, are sensitive to different physical properties (i.e. scattering, absorption and magnetic) that can provide contrast within biological tissues. Usually exogenous agents are designed with specific properties to provide contrast for these imaging methods. In nano-biotechnology there is a need to combine several of these properties into a single contrast agent. This multifunctional contrast agent can then be used by various imaging techniques simultaneously or can be used to develop new imaging modalities. We reported and characterized a multifunctional nanoparticle, made from gold nanoshells, which exhibits scattering, photothermal, photoacoustic, and magnetic properties.

History

Received Sep 07, 2011
Revised Nov 28, 2011
Published online Jan 31, 2012

Digital Object Identifier

http://dx.doi.org/10.1117/1.JBO.17.1.016015

Citation

Yeongri Jung, Guangying Guan, Chen-wei Wei, Roberto Reif, Xiaohu Gao, Matthew O’Donnell and Ruikang K. Wang, "Multifunctional nanoprobe to enhance the utility of optical based imaging techniques", J. Biomed. Opt. 17, 016015 (Jan 31, 2012); http://dx.doi.org/10.1117/1.JBO.17.1.016015