Morphometric measurement of Schlemm’s canal in normal human eye using anterior segment swept source optical coherence tomography

Shi, Guohua; Wang, Fei; Li, Xiqi; Lu, Jing; Ding, Zhihua; Sun, Xinghuai; Jiang, Chunhui; Zhang, Yudong

doi:doi:10.1117/1.JBO.17.1.016016

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Journal of Biomedical Optics / Volume 17 / Issue 1 / Research Papers: Imaging

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Morphometric measurement of Schlemm’s canal in normal human eye using anterior segment swept source optical coherence tomography

J. Biomed. Opt. 17, 016016 (Feb 09, 2012); http://dx.doi.org/10.1117/1.JBO.17.1.016016

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Abstract

References (8)

Guohua Shi, Xiqi Li, Jing Lu, and Yudong Zhang

Chinese Academy of Sciences, The Key Laboratory on Adaptive Optics, Chengdu 610209, China

Institute of Optics and Electronic, Chinese Academy of Sciences, Chengdu 610209, China

Fei Wang, Xinghuai Sun, and Chunhui Jiang

Fudan University, Department of Ophthalmology and Vision Science, Eye & ENT, Shanghai 200031, China

Zhihua Ding

Zhejiang University, State Key Laboratory of Modern Optical Instrumentation, Hangzhou 310027, China

We have used anterior segment swept source optical coherence tomography to measure Schlemm’s canal (SC) morphometric values in the living human eye. Fifty healthy volunteers with 100 normal eyes were measured in the nasal and temporal side. Comparison with the published SC morphometric values of histologic sections proves the reliability of our results. The statistical results show that there are no significant differences between nasal and temporal SC with respect to their diameter, perimeter, and area in our study (diameter: t = 0.122, p = 0.903; perimeter: t = −0.003, p = 0.998; area: t = −1.169, p = 0.244); further, no significant differences in SC morphometric values are found between oculus sinister and oculus dexter (diameter: t = 0.943, p = 0.35; perimeter: t = 1.346, p = 0.18; area: t = 1.501, p = 0.135).

History

Received Oct 11, 2011
Accepted Dec 08, 2011
Revised Dec 04, 2011
Published online Feb 09, 2012

Digital Object Identifier

http://dx.doi.org/10.1117/1.JBO.17.1.016016

Citation

Guohua Shi, Fei Wang, Xiqi Li, Jing Lu, Zhihua Ding, Xinghuai Sun, Chunhui Jiang and Yudong Zhang, "Morphometric measurement of Schlemm’s canal in normal human eye using anterior segment swept source optical coherence tomography", J. Biomed. Opt. 17, 016016 (Feb 09, 2012); http://dx.doi.org/10.1117/1.JBO.17.1.016016