Knowledge guided information fusion for segmentation of multiple sclerosis lesions in MRI images

Zhu, Chaozhe; Jiang, Tianzi

doi:doi:10.1117/12.480312

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Knowledge guided information fusion for segmentation of multiple sclerosis lesions in MRI images

Proc. SPIE 5032, 1476 (2003); http://dx.doi.org/10.1117/12.480312

Monday 17 February 2003

San Diego, CA, USA

Medical Imaging 2003: Image Processing

Milan Sonka, J. Michael Fitzpatrick

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Abstract

Chaozhe Zhu and Tianzi Jiang

Institute of Automation, CAS (China)

In this work, T1-, T2- and PD-weighted MR images of multiple sclerosis (MS) patients, providing information on the properties of tissues from different aspects, are treated as three independent information sources for the detection and segmentation of MS lesions. Based on information fusion theory, a knowledge guided information fusion framework is proposed to accomplish 3-D segmentation of MS lesions. This framework consists of three parts: (1) information extraction, (2) information fusion, and (3) decision. Information provided by different spectral images is extracted and modeled separately in each spectrum using fuzzy sets, aiming at managing the uncertainty and ambiguity in the images due to noise and partial volume effect. In the second part, the possible fuzzy map of MS lesions in each spectral image is constructed from the extracted information under the guidance of experts' knowledge, and then the final fuzzy map of MS lesions is constructed through the fusion of the fuzzy maps obtained from different spectrum. Finally, 3-D segmentation of MS lesions is derived from the final fuzzy map. Experimental results show that this method is fast and accurate.

History

Online Jul 30, 2003

Digital Object Identifier

http://dx.doi.org/10.1117/12.480312

Citation

Chaozhe Zhu and Tianzi Jiang, "Knowledge guided information fusion for segmentation of multiple sclerosis lesions in MRI images", Proc. SPIE 5032, 1476 (2003); http://dx.doi.org/10.1117/12.480312