Use of random process-based fractal measure for characterization nodules and suspicious regions in lung

Acharyya, Mausumi; Chakravarty, Sumit; Stoeckel, Jonathan

doi:doi:10.1117/12.770670

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Proceedings / Volume 6915 / Lung Nodules

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Use of random process-based fractal measure for characterization nodules and suspicious regions in lung

Proc. SPIE 6915, 69151F (2008); http://dx.doi.org/10.1117/12.770670

Tuesday 19 February 2008

San Diego, CA, USA

Medical Imaging 2008: Computer-Aided Diagnosis

Maryellen L. Giger, Nico Karssemeijer

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Abstract

References (14)

Mausumi Acharyya

Siemens Information Systems (India)

Sumit Chakravarty

Univ. of Maryland, Baltimore County

Jonathan Stoeckel

Siemens Computer Aided Diagnosis (Israel)

Chest X-ray (CXR) data is a projection image where each pixel of it represents a volumetric integration. Consequently identification of nodules and their characteristics is a difficult task in such images. Using a novel application of random process-based fractal image processing technique we extract features for nodule characterization. The uniqueness of the proposed technique lies in the fact that instead of relying on apriori information from user as in other random process inspired measures, we translate the random walk process into a feature which is based on its realization values. The Normalized Fractional Brownian Motion (NFBM) Model is derived from the random walk process. Using neighborhood region information in an incremental manner we can characterize the smoothness or roughness of a surface. The NFBM system gives a measure of roughness of a surface which in our case is a suspicious region (probable nodule). A classification procedure uses this measure to categorize nodule and non-nodule structures in the lung. The NFBM feature set is integrated in a prototype CAD system for nodule detection in CXR. Our algorithm provided a sensitivity of 75.9% with 3.1 FP/image on an independent test set of 50 CXR studies.

History

Online Mar 17, 2008

Digital Object Identifier

http://dx.doi.org/10.1117/12.770670

Citation

Mausumi Acharyya, Sumit Chakravarty and Jonathan Stoeckel, "Use of random process-based fractal measure for characterization nodules and suspicious regions in lung", Proc. SPIE 6915, 69151F (2008); http://dx.doi.org/10.1117/12.770670