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Reduction of background in optoacoustic image sequences obtained under tissue deformation

Proc. SPIE 7177, 71770Z (2009); doi:10.1117/12.810074

Sunday 25 January 2009
San Jose, CA, USA
Photons Plus Ultrasound: Imaging and Sensing 2009
Alexander A. Oraevsky, Lihong V. Wang
Michael Jaeger, Lea Siegenthaler, Michael Kitz, and Martin Frenz

Univ. Bern (Switzerland)

For real-time optoacoustic imaging of the human body, a linear array transducer and reflection mode optical irradiation is preferably used. Experimental outcomes however revealed that such a setup results in significant image background, which prevents imaging structures at the ultimate depth limited only by optical attenuation and the signal noise level. Various sources of image background such as bulk tissue absorption, reconstruction artifacts, and backscattered ultrasound could be identified. We therefore developed a novel method which results in significantly reduced background and increased imaging depth. For this purpose, we acquire in parallel a series of optoacoustic and echo-ultrasound images while the tissue sample is gradually deformed by an externally applied force. Optoacoustic signals and background signals are differently affected by the deformation and can thus be distinguished by image processing. This method takes advantage of a combined optoacoustic/echo-ultrasound device and has a strong potential for improving real-time optoacoustic imaging of deep tissue structures.

© 2009 COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.

History
Online Feb 12, 2009
Citation
Michael Jaeger, Lea Siegenthaler, Michael Kitz and Martin Frenz, "Reduction of background in optoacoustic image sequences obtained under tissue deformation", Proc. SPIE 7177, 71770Z (2009); doi:10.1117/12.810074

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