Development of a fast-scanning combined ultrasound-photoacoustic biomicroscope

Zemp, Roger J.; Lu, Huihong; Mathewson, Kory; Ranasinghesagara, Janaka; Jiang, Yan; Walsh, Andrew; Chen, Xuhui

doi:doi:10.1117/12.809296

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Proceedings / Volume 7177 / Combined Ultrasound and Optoacoustics

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Development of a fast-scanning combined ultrasound-photoacoustic biomicroscope

Proc. SPIE 7177, 717711 (2009); http://dx.doi.org/10.1117/12.809296

Sunday 25 January 2009

San Jose, CA, USA

Photons Plus Ultrasound: Imaging and Sensing 2009

Alexander A. Oraevsky, Lihong V. Wang

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Abstract

References (14)

Roger J. Zemp, Huihong Lu, Kory Mathewson, Janaka Ranasinghesagara, Yan Jiang, Andrew Walsh, and Xuhui Chen

Univ. of Alberta (Canada)

Recently a realtime photoacoustic microscopy system has been demonstrated. Unfortunately, however, displayed B-scan images were sometimes difficult to interpret as there was little structural context. In this work, we provide structural context for photoacoustic microscopy images by adding ultrasound biomicroscopy as a complementary and synergistic modality. Our system uses a voice-coil translation stage capable of 1" lateral translation, and can operate in excess of 15 Hz for 1-cm translations, providing up to 30 ultrasound frames per second. The frame-rate of the photoacoustic acquisitions is limited by the 20-Hz pulse-repetition rate of the laser, but can be increased with a faster-repetition-rate laser. Data from the system is streamed in real time from a 2GS/s PCI data acquisition card to the host PC at rates as high as 200 MB/s. The system should prove useful for various in vivo studies, including combined ultrasound Doppler and photoacoustic imaging.

History

Online Feb 24, 2009

Digital Object Identifier

http://dx.doi.org/10.1117/12.809296

Citation

Roger J. Zemp, Huihong Lu, Kory Mathewson, Janaka Ranasinghesagara, Yan Jiang, Andrew Walsh and Xuhui Chen, "Development of a fast-scanning combined ultrasound-photoacoustic biomicroscope", Proc. SPIE 7177, 717711 (2009); http://dx.doi.org/10.1117/12.809296