Quantum technologies harness nonclassical features of particles, here, photons, to develop novel, efficient, and precise devices for information processing applications. Superposition, entanglement, as well as the coherent manipulation of quantum states are at the heart of the second quantum revolution (quantum 2.0) which targets the development of secure cryptographic systems, complex computation protocols, and more. Emerging quantum architectures rely on the realistic implementation of photonic schemes which are scalable, resource-efficient, and compatible with CMOS technologies as well as fiber networks. This work demonstrates current schemes utilized for time-/frequency-bin entanglement generation and processing by leveraging existing telecommunications and integrated photonics infrastructures.
KEYWORDS: Holmium, Current controlled current source, Visualization, Blood circulation, Doppler tomography, Optical coherence tomography, Optical testing, Eye, In vivo imaging
Visually evoked changes of retinal blood flow can serve as an important research tool to investigate eye disease such as glaucoma and diabetic retinopathy. In this study we used a combined, research-grade, high-resolution Doppler OCT+ERG system to study changes in the retinal blood flow (RBF) and retinal neuronal activity in response to visual stimuli of different intensities, durations and type (flicker vs single flash). Specifically, we used white light stimuli of 10 ms and 200 ms single flash, 1s and 2s for flickers stimuli of 20% duty cycle. The study was conducted in-vivo in pigmented rats. Both single flash (SF) and flicker stimuli caused increase in the RBF. The 10 ms SF stimulus did not generate any consistent measurable response, while the 200 ms SF of the same intensity generated ~4% change in the RBF peaking at ~1.5 s after the stimulus onset. Single flash stimuli introduced ~2x smaller change in RBF and ~30% earlier RBF peak response compared to flicker stimuli of the same intensity and duration. Doubling the intensity of SF or flicker stimuli increased the RBF peak magnitude by ~1.5x. Shortening the flicker stimulus duration by 2x increased the RBF recovery rate by 2x, however, had no effect on the rate of RBF change from baseline to peak.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.