This paper details the design and fabrication of an integrated optical waveguide biosensor for
antibody/antigen detection. SU-8 polymer is used as the core material to have a bi-conical tapered
waveguide fabricated on a silicon substrate. PDMS is used as a buffer layer. The waist diameter of the biconical
tapered waveguide has been optimized using Opti-BPM CAD software before fabrication. In
addition, the fabrication technique employs simultaneous and single-step formation of the polymer
waveguide structures for the guidance of light with V-grooves for low-cost passive alignment of glass
optical fiber. The designed biosensor chip demonstrates sensing of FITC tagged goat anti human IgG
(GaHIgG) and HIgG immobilized over the sensor surface was the bio receptor. The sensor uses the
evanescent field that is present at the surface of the core for rapid and accurate sensing of
antibody/antigen in the range of few micrograms per ml.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.