Ms. Katrien Houbrechts Profile

Katrien Houbrechts

at KU Leuven

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Publications (7)

Proceedings Article | 29 May 2024 Paper

Characterization of invasive breast cancer lesions in breast x-ray imaging: a reference dataset for virtual imaging trials

M. Keupers, K. Houbrechts, L. Cockmartin, H. Bosmans, C. Van Ongeval

Proceedings Volume 13174, 131741K (2024) https://doi.org/10.1117/12.3026999

KEYWORDS: Digital breast tomosynthesis, Breast, Visibility, Breast density, Cancer detection, Cancer, Breast cancer, Magnetic resonance imaging, X-ray imaging, Ultrasonography

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Proceedings Article | 29 May 2024 Paper

Applicability of virtual breast phantoms for detectability studies in synthetic mammography

Katrien Houbrechts, Liesbeth Vancoillie, Lesley Cockmartin, Nicholas Marshall, Hilde Bosmans

Proceedings Volume 13174, 131741B (2024) https://doi.org/10.1117/12.3026975

KEYWORDS: Breast, Digital breast tomosynthesis, Breast density, Mammography

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Proceedings Article | 1 April 2024 Presentation + Paper

Improved isotropic resolution and small detail detectability in a digital breast tomosynthesis system with flying focal spot technology

Katrien Houbrechts, Nicholas Marshall, Lesley Cockmartin, Hilde Bosmans

Proceedings Volume 12925, 129250N (2024) https://doi.org/10.1117/12.3005765

KEYWORDS: Digital breast tomosynthesis, Modulation transfer functions, X-ray technology, Motion blur, Imaging systems

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There are two main acquisition modes for acquiring digital breast tomosynthesis (DBT) projection data: continuous mode and step-and-shoot mode. This work characterizes a new x-ray tube with flying focal spot (FFS) technology, designed to compensate for the continuous focus motion during exposure. The image sharpness of an established wide-angle DBT system with moving focus during exposure (the current standard) and a newly introduced FFS x-ray tube was assessed using the modulation transfer function (MTF). The spatial frequency for the 25% MTF value (f_25%) was measured at 2, 4 and 6cm above the table. The impact on the visibility of calcification-like test objects was investigated with the CDMAM phantom that was positioned at various heights above the table. The threshold gold thickness (T_t) was calculated for the 0.1 mm discs. For the moving focus system, f_25% measured at 2, 4 and 6cm in the 0° DBT projection fell by 35%, 49% and 59% in the tube-travel direction compared to figures of 7.6, 6.8, and 6.6 mm^-1 for the FFS system. In the frontback direction, f_25% was 7.4, 7.3 and 7.2 mm^-1 at 2, 4 and 6cm, respectively for the moving focus unit while for the FFS system, these figures were 7.1, 6.7 and 5.9 mm^-1. There was no significant difference in f_25% for the front-back and tube-travel directions for the FFS unit (p<0.04). The T_t values at 4cm and 6cm above the table in DBT mode improved by 33% and 52%, respectively for the FFS system versus the moving focus system. The improvement in T_t increased as object height above the table increased. The FFS system has a reduced DBT scan time compared to the moving focus system (4.8s vs 21.7s) which is expected to reduce patient motion artefacts. The FFS system has in DBT mode an improved isotropic resolution, improved small detail detectability and faster total scan times. Therefore, this new DBT system has the potential for increased microcalcification detection and patient throughput compared to its predecessors.

Proceedings Article | 7 April 2023 Poster + Paper

3D-GAN to generate representative and realistic three-dimensional breast cancer models for virtual clinical trial applications

R. Das, K. Koukoutegos, Y. Wang, M. Keupers, H. Bosmans, K. Houbrechts

Proceedings Volume 12463, 124632G (2023) https://doi.org/10.1117/12.2653561

KEYWORDS: 3D modeling, Tumor growth modeling, Data modeling, Image segmentation, Breast, Digital breast tomosynthesis, Simulations, Cancer

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Proceedings Article | 7 April 2023 Presentation + Paper

A complete procedure to prepare virtual clinical trials in digital breast tomosynthesis

K. Houbrechts, R. Das, M. Keupers, L. Vancoillie, L. Cockmartin, N. Marshall, H. Bosmans

Proceedings Volume 12463, 124631C (2023) https://doi.org/10.1117/12.2653551

KEYWORDS: Digital breast tomosynthesis, Breast, Tumor growth modeling, Computer simulations, Cancer, Image segmentation

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Proceedings Article | 15 February 2021 Presentation + Paper

Virtual clinical trial platforms for digital breast tomosynthesis: a local solution compared to the VICTRE platform

K. Houbrechts, L. Vancoillie, L. Cockmartin, N. Marshall, H. Bosmans

Proceedings Volume 11595, 115951I (2021) https://doi.org/10.1117/12.2581742

KEYWORDS: Digital breast tomosynthesis, Clinical trials, Reconstruction algorithms, Visualization, Visual analytics, Breast

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Proceedings Article | 15 February 2021 Presentation + Paper

The creation of a breast cancer voxel model database for virtual clinical trials in digital breast tomosynthesis

L. Vancoillie, K. Houbrechts, J. Vignero, M. Keupers, L. Cockmartin, N. Marshall, Hilde Bosmans

Proceedings Volume 11595, 115950P (2021) https://doi.org/10.1117/12.2581741

KEYWORDS: Digital breast tomosynthesis, Tumor growth modeling, Clinical trials, Breast cancer, Databases, Data modeling, Cancer, Systems modeling, Visual process modeling, Image segmentation

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Showing 5 of 7 publications

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