Pancreatic cancer is one of the most feared cancer types due to high death rates and the difficulty to perform surgery. This cancer outcome could benefit from recent technological developments for diagnosis. We used a combination of standard Full Field OCT and Dynamic Full Field OCT to capture both morphological features and metabolic functions of rodents pancreas in normal and cancerous conditions with and without chemotherapy. Results were compared to histology to evaluate the performances and the specificities of the method. The comparison highlighted the importance of a number of endogenous markers like immune cells, fibrous development, architecture and more.

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Clement Apelian, Marine Camus, Frederic Prat, and A. Claude Boccara, "Pancreatic cancer study based on full field OCT and dynamic full field OCT (Conference Presentation)," Proc. SPIE 10054, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV, 100540N (Presented at SPIE BiOS: January 30, 2017; Published: 18 April 2017); https://doi.org/10.1117/12.2252065.5371718630001.