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12 May 2022 Handheld Point-of-Care Device for the Quantification of Anti-SARS-CoV-2 Antibodies
Damber Thapa, Nakisa Samadi, Nima Tabatabaei
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Proceedings Volume PC11968, Optical Diagnostics and Sensing XXII: Toward Point-of-Care Diagnostics; PC1196803 (2022) https://doi.org/10.1117/12.2607778
Event: SPIE BiOS, 2022, San Francisco, California, United States
Abstract
Antibodies that are produced following infection due to the SARS-CoV-2 virus or vaccination are critical for monitoring the immune response of an individual or the impact of the vaccine over time. As vaccines become available, there is a need for rapid, accurate, and low-cost point-of-care tools for monitoring the effectiveness of the vaccines over time at the population level. Here, we report the efficiency of a handheld point-of-care thermo-photonic device for quantifying anti-SARS-CoV-2 antibodies in humanized control positive solution. Results showed that the imager in conjunction with rapid diagnostic tests (RDT) can detect and quantify antibody levels within clinically relevant range and with a limit of detection of 0.1 µg/ml.
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Damber Thapa, Nakisa Samadi, and Nima Tabatabaei "Handheld Point-of-Care Device for the Quantification of Anti-SARS-CoV-2 Antibodies", Proc. SPIE PC11968, Optical Diagnostics and Sensing XXII: Toward Point-of-Care Diagnostics, PC1196803 (12 May 2022); https://doi.org/10.1117/12.2607778
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KEYWORDS
Point-of-care devices
Standards development
Infrared imaging
Infrared radiation
Infrared sensors
Nanoparticles
Plasma
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