Tissue classification during colorectal cancer surgery using diffuse reflectance spectroscopy at the fingertip: design and performance of a compact side-firing probe

Freija Geldof; Mark Witteveen; Henricus Sterenborg; Behdad Dashtbozorg; Theo Ruers

doi:10.1117/12.2650113

7 March 2023 Tissue classification during colorectal cancer surgery using diffuse reflectance spectroscopy at the fingertip: design and performance of a compact side-firing probe

Freija Geldof, Mark Witteveen, Henricus Sterenborg, Behdad Dashtbozorg, Theo Ruers

Author Affiliations +

Proceedings Volume PC12376, Optical Tomography and Spectroscopy of Tissue XV; PC123760M (2023) https://doi.org/10.1117/12.2650113
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Optical technologies are widely used for tissue sensing purposes, however maneuvering conventional probe designs with flat-tipped fibers in narrow spaces can be challenging, such as in pelvic colorectal cancer surgery. In this study, a compact side-firing fiber probe was developed for tissue discrimination during colorectal cancer surgery using diffuse reflectance spectroscopy. The light behavior was compared to flat-tipped fibers using both Monte Carlo simulations and the tissue classification performance was examined using freshly excised colorectal cancer specimens. Using the developed probe and classification algorithm, we achieved an accuracy of 0.92 for the discrimination of colorectal tumor tissue from healthy tissue.

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Freija Geldof, Mark Witteveen, Henricus Sterenborg, Behdad Dashtbozorg, and Theo Ruers "Tissue classification during colorectal cancer surgery using diffuse reflectance spectroscopy at the fingertip: design and performance of a compact side-firing probe ", Proc. SPIE PC12376, Optical Tomography and Spectroscopy of Tissue XV, PC123760M (7 March 2023); https://doi.org/10.1117/12.2650113

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