PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
Obtaining high resolution images in scattering tissue has been a long-standing challenge in microscopy. This challenge is exacerbated when high frame rates are required, or when 3D imaging is required over extended volumes. I will present several tools we have developed to address this challenge. These can be applied to a variety of microscopy modalities ranging from multiplane imaging with speckle, to multi-focus confocal imaging with targeted illumination, and finally to multiphoton imaging. Our main applications are in-vivo imaging in the mouse brain, where we demonstrate high contrast kHz-rate imaging of neuronal electrical activity and blood flow deep in tissue.
Jerome Mertz
"Fast volumetric imaging in tissue", Proc. SPIE PC12848, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXXI, PC1284805 (13 March 2024); https://doi.org/10.1117/12.3016422
ACCESS THE FULL ARTICLE
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
The alert did not successfully save. Please try again later.
Jerome Mertz, "Fast volumetric imaging in tissue," Proc. SPIE PC12848, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXXI, PC1284805 (13 March 2024); https://doi.org/10.1117/12.3016422