Feasibility study of spatial frequency domain imaging using a handheld miniaturized projector and rigid endoscope

Sreyankar Nandy; Mohsen Erfanzadeh; Feifei Zhou; Quing Zhu

doi:10.1117/12.2253221

27 March 2017 Feasibility study of spatial frequency domain imaging using a handheld miniaturized projector and rigid endoscope

Sreyankar Nandy, Mohsen Erfanzadeh, Feifei Zhou, Quing Zhu

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Proceedings Volume 10059, Optical Tomography and Spectroscopy of Tissue XII; 100591S (2017) https://doi.org/10.1117/12.2253221
Event: SPIE BiOS, 2017, San Francisco, California, United States

Abstract

Initial feasibility of a spatial frequency domain imaging system was studied consisting of a hand held miniaturized projector and a rigid endoscope. Three wavelengths and two spatial frequencies were used for imaging. The system was calibrated using tissue mimicking phantoms. In vivo imaging was performed on five live mouse tumor models, and the absorption, scattering, hemoglobin oxygen saturation was measured. The initial promising results indicate that the spatial frequency domain imaging can a very useful tool for quantitative wide field tissue evaluation during minimally invasive image guided surgery.

Citation Download Citation

Sreyankar Nandy, Mohsen Erfanzadeh, Feifei Zhou, and Quing Zhu "Feasibility study of spatial frequency domain imaging using a handheld miniaturized projector and rigid endoscope", Proc. SPIE 10059, Optical Tomography and Spectroscopy of Tissue XII, 100591S (27 March 2017); https://doi.org/10.1117/12.2253221

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