Julian Moosmann,1 Berit Zeller-Plumhoff,1 D. C. Florian Wieland,1 Silvia Galli,2 Diana Krüger,1 Thomas Dose,1 Hilmar Burmester,1 Fabian Wilde,1 Martin Bech,3 Niccolò Peruzzi,3 Björn Wiese,1 Alexander Hipp,1 Felix Beckmann,1 Jörg Hammel,1 Regine Willumeit-Römer1,4
1Helmholtz-Zentrum Geesthacht (Germany) 2Malmö Univ. (Sweden) 3Lund Univ. (Sweden) 4Christian-Albrechts-Univ. zu Kiel (Germany)
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
Permanent implants made of titanium or its alloys are the gold standard in many orthopedic and traumatological
applications due to their good biocompatibility and mechanical properties. However, a second surgical intervention is
required for this kind of implants as they have to be removed in the case of children that are still growing or on patient’s
demand. Therefore, magnesium-based implants are considered for medical applications as they are degraded under
physiological conditions. The major challenge is tailoring the degradation in a manner that is suitable for a biological
environment and such that stabilization of the bone is provided for a controlled period. In order to understand failure
mechanisms of magnesium-based implants in orthopedic applications and, further, to better understand the
osseointegration, screw implants in bone are studied under mechanical load by means of a push-out device installed at
the imaging beamline P05 of PETRA III at DESY. Conventional absorption contrast microtomography and phasecontrast
techniques are applied in order to monitor the bone-to-implant interface under increasing load conditions. In this
proof-of-concept study, first results from an in situ push-out experiment are presented.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
The alert did not successfully save. Please try again later.
Julian Moosmann, Berit Zeller-Plumhoff, D. C. Florian Wieland, Silvia Galli, Diana Krüger, Thomas Dose, Hilmar Burmester, Fabian Wilde, Martin Bech, Niccolò Peruzzi, Björn Wiese, Alexander Hipp, Felix Beckmann, Jörg Hammel, Regine Willumeit-Römer, "Biodegradable magnesium-based implants in bone studied by synchrotron radiation microtomography," Proc. SPIE 10391, Developments in X-Ray Tomography XI, 103910O (26 September 2017); https://doi.org/10.1117/12.2275121