Depth resolved quantitative profiling of stratum corneum lipids and water content using short-wave infrared spectroscopy

Anna Ezerskaia; Silvania F. Pereira; H. Paul Urbach; Babu Varghese

doi:10.1117/12.2291896

14 February 2018 Depth resolved quantitative profiling of stratum corneum lipids and water content using short-wave infrared spectroscopy

Anna Ezerskaia, Silvania F. Pereira, H. Paul Urbach, Babu Varghese

Author Affiliations +

Proceedings Volume 10467, Photonics in Dermatology and Plastic Surgery 2018; 104670R (2018) https://doi.org/10.1117/12.2291896
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

We show the feasibility of short wave infrared spectroscopy combined with tape stripping as a simple and noninvasive method for the analysis of lipids and the degree of hydration as a function of depth in the stratum corneum. The spectroscopic method utilizes differential detection with three wavelengths 1720, 1750, and 1770 nm, corresponding to the lipid vibrational bands that lay “in between” the prominent water absorption bands. The results are compared with other biophysical devices such as Corneometer and Sebumeter.

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Citation Download Citation

Anna Ezerskaia, Silvania F. Pereira, H. Paul Urbach, and Babu Varghese "Depth resolved quantitative profiling of stratum corneum lipids and water content using short-wave infrared spectroscopy", Proc. SPIE 10467, Photonics in Dermatology and Plastic Surgery 2018, 104670R (14 February 2018); https://doi.org/10.1117/12.2291896

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