Towards wide-field imaging of brain slices using a quantum diamond microscope (Conference Presentation)

Adam Wojciechowski; Mursel Karadas; Louise Frellsen; Axel Thielscher; Nils Ole Dalby; Alexander Huck; Ulrik Lund Andersen

doi:10.1117/12.2325262

6 November 2018 Towards wide-field imaging of brain slices using a quantum diamond microscope (Conference Presentation)

Adam Wojciechowski, Mursel Karadas, Louise Frellsen, Axel Thielscher, Nils Ole Dalby, Alexander Huck, Ulrik Lund Andersen

Author Affiliations +

Proceedings Volume 10771, Quantum Communications and Quantum Imaging XVI; 1077103 (2018) https://doi.org/10.1117/12.2325262
Event: SPIE Optical Engineering + Applications, 2018, San Diego, California, United States

Abstract

Unravelling the mysteries of the complex neural network dynamics of the brain is of utmost importance to science as it might lead to a deeper understanding of perception, cognition and consciousness. Numerous techniques are being used for brain imaging including intracellular electrophysiology, calcium imaging and microelectrode arrays imaging. However, all these technologies are facing severe limitations in the spatio-temporal resolutions and are thus unable to resolve fast real-time single neuron activity over a larger area of the brain. I will discuss our recent efforts in developing a new technique for neuroscience that offer wide-field brain imaging with unprecedented spatio-temporal resolution. It is based on magnetic field sensing of the neuron activity using magneto-optically sensitive Nitrogen-Vacancy color centers in a diamond crystal combined with light microscopy.

Conference Presentation

Citation Download Citation

Adam Wojciechowski, Mursel Karadas, Louise Frellsen, Axel Thielscher, Nils Ole Dalby, Alexander Huck, and Ulrik Lund Andersen "Towards wide-field imaging of brain slices using a quantum diamond microscope (Conference Presentation)", Proc. SPIE 10771, Quantum Communications and Quantum Imaging XVI, 1077103 (6 November 2018); https://doi.org/10.1117/12.2325262

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