Temperature detection by photoacoustic for nanoprobe-mediated photothermal therapy

Siyu Liu; Feifan Zhou; Yue Zhao; Liwei Liu; Junle Qu; Wei R. Chen

doi:10.1117/12.2507030

7 March 2019 Temperature detection by photoacoustic for nanoprobe-mediated photothermal therapy

Siyu Liu, Feifan Zhou, Yue Zhao, Liwei Liu, Junle Qu, Wei R. Chen

Author Affiliations +

Proceedings Volume 10879, Biophotonics and Immune Responses XIV; 108790R (2019) https://doi.org/10.1117/12.2507030
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

Photothermal therapy is a tumor target therapy, which can induce temperature increase by laser in tumor tissue to eliminate cancer cells, without affecting surrounding healthy tissue. The temperature distribution in the tumor tissue directly determine the therapeutic efficacy. Therefore, real-time temperature monitoring is particularly important during photothermal therapy. However, accurate real-time temperature measurements in deep tissue still face many obstacles. This paper shows the feasibility of photoacoustic technology for real-time temperature monitoring with or without nanomaterials as photoacoustic contrast agents.

Citation Download Citation

Siyu Liu, Feifan Zhou, Yue Zhao, Liwei Liu, Junle Qu, and Wei R. Chen "Temperature detection by photoacoustic for nanoprobe-mediated photothermal therapy", Proc. SPIE 10879, Biophotonics and Immune Responses XIV, 108790R (7 March 2019); https://doi.org/10.1117/12.2507030

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