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GaInAsP photonic crystal nanolaser is a tiny semiconductor laser simply fabricated and operated by photopumping. It is applicable to sensing because it changes its lasing characteristics when some media is directly attached to the cavity. We have demonstrated the sensing of liquids and biomolecules with ultrahigh sensitivity. Such sensitivity was first thought to arise from the index of the media. But we found that this device has the ion sensitivity in addition to the conventional index sensitivity. It was confirmed from various evidence of bio-chemical sensing experiments. It achieves a very simple sensing of CRMP2 protein, a candidate biomarker for Alzheimer's disease only by using a pump source and PD to detect the emission intensity change. It was also found that the emission intensity and wavelength are controllable in a photoelectrochemical circuit, which can be a novel laser engineering.
Toshihiko Baba
"Iontronic sensing using photonic crystal nanolasers (Conference Presentation)", Proc. SPIE 10927, Photonic and Phononic Properties of Engineered Nanostructures IX, 109271S (8 March 2019); https://doi.org/10.1117/12.2515982
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