Optoelectronic method for the determination of synthetic cannabinoids and their metabolites

Monica Ionica Streche; Georgeta Marcela Bican; Jeni Carla Colev; Mihai Radu; Raluca-Andreea Băjănaru; Paul Şchiopu; Marian Vlădescu; Radu Macovei; Mihai  Ionică

doi:10.1117/12.2324798

31 December 2018 Optoelectronic method for the determination of synthetic cannabinoids and their metabolites

Monica Ionica Streche, Georgeta Marcela Bican, Jeni Carla Colev, Mihai Radu, Raluca-Andreea Băjănaru, Paul Şchiopu, Marian Vlădescu, Radu Macovei, Mihai Ionică

Author Affiliations +

Proceedings Volume 10977, Advanced Topics in Optoelectronics, Microelectronics, and Nanotechnologies IX; 109773K (2018) https://doi.org/10.1117/12.2324798
Event: Advanced Topics in Optoelectronics, Microelectronics and Nanotechnologies IX, 2018, Constanta, Romania

Abstract

Establishing an optoelectronic method for the determination of synthetic cannabinoids and their metabolites is necessary because synthetic cannabinoids are a group of psychoactive compounds designed to mimic the effects of marijuana. These compounds are usually sprayed on natural plants in order to be smoked. Several synthetic cannabinoids can be found on these smoked plants simultaneously. Their effective dose is lower than that of natural marijuana but with high psychoactive potency [1]. Due to their high potential for abuse and availability, these compounds are considered to be narcotic drugs. Thus, there has been an increased demand for the development of sensitive, reliable, robust and sustainable analytical methods for the identification and quantification of these compounds by clinical, forensic and toxicological laboratories [2].

The method presented in the paper will be based on liquid chromatography with a mass spectrometer detector (LCMS/ MS). The paper aims to obtain, using the developed method, the mass spectra of synthetic cannabinoids and their metabolites. The mass spectrum represents the relative abundance of ions resulting from an ionization process of a family of molecules. This is a unique feature for each compound, which allows identification of a substance from a matrix of unknown substances [3].

Citation Download Citation

Monica Ionica Streche, Georgeta Marcela Bican, Jeni Carla Colev, Mihai Radu, Raluca-Andreea Băjănaru, Paul Şchiopu, Marian Vlădescu, Radu Macovei, and Mihai Ionică "Optoelectronic method for the determination of synthetic cannabinoids and their metabolites", Proc. SPIE 10977, Advanced Topics in Optoelectronics, Microelectronics, and Nanotechnologies IX, 109773K (31 December 2018); https://doi.org/10.1117/12.2324798

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available