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Ultrafast laser ablation may provide treatment for vocal fold (VF) scarring. Optical properties of VF must be known prior to clinical implementation to select appropriate laser surgery conditions. We present scattering lengths and ablation thresholds of human and canine tissues measured using an experimental approach which involves an image-guided, laser-ablation based method. We study effects of tissue storage and cumulative pulse overlap on scattering properties and ablation thresholds. We perform deep tissue ablation using moderate numerical apertures and multiple laser operating conditions to imitate predicted surgical implementation. Results provide guidelines for clinical implementation towards VF restoration therapy.
Liam P. Andrus,Adela Ben-Yakar, andTed Mau M.D.
"Scattering properties and femtosecond laser ablation thresholds of human and canine vocal folds (Conference Presentation)", Proc. SPIE 11270, Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XX, 1127007 (9 March 2020); https://doi.org/10.1117/12.2547163
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Liam P. Andrus, Adela Ben-Yakar, Ted Mau M.D., "Scattering properties and femtosecond laser ablation thresholds of human and canine vocal folds (Conference Presentation)," Proc. SPIE 11270, Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XX, 1127007 (9 March 2020); https://doi.org/10.1117/12.2547163