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5 March 2021 Paced breathing hemodynamics in breast tumors measured with a high-optode density wearable diffuse optical probe
Samuel Spink, Adam Eggebrecht, Naomi Ko, Darren M. Roblyer
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Proceedings Volume 11622, Multiscale Imaging and Spectroscopy II; 116220L (2021) https://doi.org/10.1117/12.2577266
Event: SPIE BiOS, 2021, Online Only
Abstract
We present an update on our high optode-density continuous-wave (CW) wearable diffuse optical device for the investigation of hemodynamic responses of locally advanced breast tumors during neoadjuvant chemotherapy (NAC). The device consists of a rigid-flex substrate with 32 LEDs at two wavelengths and 16 detectors. Measurements during a cuff occlusion indicate that the probe can quantify hemodynamics temporally, and measurements on spatially-complex flow phantoms have validated the ability to reconstruct spatial contrast. A normal volunteer study is currently ongoing, and preliminary results (N=7 volunteers) indicate that paced breathing hemodynamics can be quantified in healthy subjects.
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Samuel Spink, Adam Eggebrecht, Naomi Ko, and Darren M. Roblyer "Paced breathing hemodynamics in breast tumors measured with a high-optode density wearable diffuse optical probe", Proc. SPIE 11622, Multiscale Imaging and Spectroscopy II, 116220L (5 March 2021); https://doi.org/10.1117/12.2577266
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KEYWORDS
Hemodynamics
Breast
Tumors
Synthetic aperture radar
Cancer
Continuous wave operation
Light emitting diodes
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