Quantification of peritumoral white matter damage using cross-polarization OCT

Konstantin S. Yashin; Ksenia A. Achkasova; Alexander A. Moiseev; Elena B. Kiseleva; Evgenia L. Bederina; Anna A. Epishkina; Anton Yu. Ermolaev; Igor A. Medyanik; Elena V. Zagaynova; Natalia D. Gladkova

doi:10.1117/12.2578274

5 March 2021 Quantification of peritumoral white matter damage using cross-polarization OCT

Konstantin S. Yashin, Ksenia A. Achkasova, Alexander A. Moiseev, Elena B. Kiseleva, Evgenia L. Bederina, Anna A. Epishkina, Anton Yu. Ermolaev, Igor A. Medyanik, Elena V. Zagaynova, Natalia D. Gladkova

Author Affiliations +

Proceedings Volume 11629, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics; 116290V (2021) https://doi.org/10.1117/12.2578274
Event: SPIE BiOS, 2021, Online Only

Abstract

Cross-polarization (CP) OCT is a so-called functional extension of OCT that seems to have benefits in visualization of myelin. During surgery it may be quite useful receiving information concerning myelination rate in white matter surrounding tumor mass. It this study it was shown that the quantification of peritumoral white matter using pseudocolor en-face OCT maps based on three optical coefficients (the rate of attenuation in the co- and cross-channel, and the interchannel attenuation difference) correlated well with histological data. Therefore, accurate quantitative CP OCT assessment of peritumoral white matter condition supports the developing the intraoperative implementation of this method.

Conference Presentation

Citation Download Citation

Konstantin S. Yashin, Ksenia A. Achkasova, Alexander A. Moiseev, Elena B. Kiseleva, Evgenia L. Bederina, Anna A. Epishkina, Anton Yu. Ermolaev, Igor A. Medyanik, Elena V. Zagaynova, and Natalia D. Gladkova "Quantification of peritumoral white matter damage using cross-polarization OCT", Proc. SPIE 11629, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics, 116290V (5 March 2021); https://doi.org/10.1117/12.2578274

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available