Labeling enhancement of hydrophilic and hydrophobic molecules in tissue sections

Paul Tseng; Shu-Jen Chiang; Shean-Jen Chen; Chen-Yuan Dong

doi:10.1117/12.2582702

22 March 2021 Labeling enhancement of hydrophilic and hydrophobic molecules in tissue sections

Paul Tseng, Shu-Jen Chiang, Shean-Jen Chen, Chen-Yuan Dong

Proceedings Volume 11648, Multiphoton Microscopy in the Biomedical Sciences XXI; 116481E (2021) https://doi.org/10.1117/12.2582702
Event: SPIE BiOS, 2021, Online Only

Conference Poster

Abstract

In this study, the efficiency of uni- and bi-directional molecular diffusion in porcine liver tissue sections was studied. Tissue sections on the order of a few hundred microns in thickness were used. We found that bi-directional diffusion is more efficient in delivering probe molecules. Therefore, bi-directional labeling is useful in visualizing tissue architecture in three-dimensions.

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Citation Download Citation

Paul Tseng, Shu-Jen Chiang, Shean-Jen Chen, and Chen-Yuan Dong "Labeling enhancement of hydrophilic and hydrophobic molecules in tissue sections", Proc. SPIE 11648, Multiphoton Microscopy in the Biomedical Sciences XXI, 116481E (22 March 2021); https://doi.org/10.1117/12.2582702

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