Simulation of ablation and thermal damage in CO2 laser-irradiated tissue

Miron Gerstmann; A. M. Sagi; Ariella Avidor; Abraham Katzir; Solange Akselrod

doi:10.1117/12.17639

1 June 1990 Simulation of ablation and thermal damage in CO₂ laser-irradiated tissue

Miron Gerstmann, A. M. Sagi, Ariella Avidor, Abraham Katzir, Solange Akselrod

Proceedings Volume 1202, Laser-Tissue Interaction; (1990) https://doi.org/10.1117/12.17639
Event: OE/LASE '90, 1990, Los Angeles, CA, United States

Abstract

A previously described numerical model which calculates heat transfer in biological tissue exposed to Co2 laser irradiation was adapted and applied to predict the amount of ablated tissue and peripheral damage under high power pulsed irradiation. The main object of this work is to search for the irradiation parameters which minimize damage. Simulations of pulsed irradiation were carried out employing rabbit brain tissue thermal constants and varying the following irradiation parameters: pulse duration, repetition rate of the pulse train and beam profile. A Gaussian profile with a beam radius of 1mm was employed over a series of l5OmJ single pulses differing in duration. An optimal value of lms for pulse length was obtained. No improvement was observed at lower durations. Next, the pulse length was kept constant and the effect of the repetition rate of a pulse train was investigated. The damaged volume was shown to increase with repetition rate, however, at very high repetition rates damage decreased to the minimal values observed for the low range of repetition rates. Similar procedures carried out using a rectangular beam profile showed that lateral damage reduced to widths of a few microns with pulse lengths shorter than ims. In addition, ablation thresholds and ablation rates were calculated for both profiles. The theoretical values obtained agree with previous experimental results.

Citation Download Citation

Miron Gerstmann, A. M. Sagi, Ariella Avidor, Abraham Katzir, and Solange Akselrod "Simulation of ablation and thermal damage in CO₂ laser-irradiated tissue", Proc. SPIE 1202, Laser-Tissue Interaction, (1 June 1990); https://doi.org/10.1117/12.17639

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