Digital microscopic mapping of laser induced polarization ellipticity maps in differential diagnostics of preparations of benign and malignant prostate tumours

L. Trifonyuk; A. Strashkevich; S. Kozlov; I. Davidenko; I. Poliansky; N. Pavlyukovich; A. Pavlyukovich; Yu. Tomka; I. V. Fesiv; Yu. A. Ushenko; M. Talakh; P. A. Gorodenskiy; V. K. Gantyuk

doi:10.1117/12.2616835

20 December 2021 Digital microscopic mapping of laser induced polarization ellipticity maps in differential diagnostics of preparations of benign and malignant prostate tumours

L. Trifonyuk, A. Strashkevich, S. Kozlov, I. Davidenko, I. Poliansky, N. Pavlyukovich, A. Pavlyukovich, Yu. Tomka, I. V. Fesiv, Yu. A. Ushenko, M. Talakh, P. A. Gorodenskiy, V. K. Gantyuk

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Proceedings Volume 12126, Fifteenth International Conference on Correlation Optics; 1212627 (2021) https://doi.org/10.1117/12.2616835
Event: Fifteenth International Conference on Correlation Optics, 2021, Chernivtsi, Ukraine

Abstract

The article presents the results of a study of the possibilities of 3D Stokes-polarimetric mapping of microscopic images of protein fluorofors of the prostate. Polarization-holographic measurement and analysis of layer-by-layer maps and histograms of the distribution of the polarization ellipticity of microscopic images of biological preparations of the prostate. Determination of the relationship between statistical moments of the 1st - 4th orders, which characterize layer-by-layer maps of distributions of the polarization ellipticity of microscopic images of biological preparations of the prostate and pathological conditions of the prostate. Determination of the operational characteristics (sensitivity, specificity, accuracy) of the diagnostic strength of the 3D layer-by-layer Stokes polarimetric mapping method.

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L. Trifonyuk, A. Strashkevich, S. Kozlov, I. Davidenko, I. Poliansky, N. Pavlyukovich, A. Pavlyukovich, Yu. Tomka, I. V. Fesiv, Yu. A. Ushenko, M. Talakh, P. A. Gorodenskiy, and V. K. Gantyuk "Digital microscopic mapping of laser induced polarization ellipticity maps in differential diagnostics of preparations of benign and malignant prostate tumours", Proc. SPIE 12126, Fifteenth International Conference on Correlation Optics, 1212627 (20 December 2021); https://doi.org/10.1117/12.2616835

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