UV-FPM for the label-free analysis of biological samples

M. Dethlefsen; M. Azhar; T. Engel; J. Abhijeet; P. Paulicka; M. Kollegal; G. Marquardt

doi:10.1117/12.2661540

16 March 2023 UV-FPM for the label-free analysis of biological samples

M. Dethlefsen, M. Azhar, T. Engel, J. Abhijeet, P. Paulicka, M. Kollegal, G. Marquardt

Proceedings Volume 12391, Label-free Biomedical Imaging and Sensing (LBIS) 2023; 123910D (2023) https://doi.org/10.1117/12.2661540
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Currently, biological samples that are analyzed microscopically such as blood smears or tissue sections need to be stained to visualize important information such cell nuclei. This represents a major hurdle on the path to further automation, increases costs and can lead to significant lab-to-lab variation in terms of diagnostic results. Here, the authors will present a novel microscopy approach, based on UV Fourier Ptychography Microscopy, that is able to directly image blood smears and digital pathology samples without the need for staining.

Conference Presentation

Citation Download Citation

M. Dethlefsen, M. Azhar, T. Engel, J. Abhijeet, P. Paulicka, M. Kollegal, and G. Marquardt "UV-FPM for the label-free analysis of biological samples", Proc. SPIE 12391, Label-free Biomedical Imaging and Sensing (LBIS) 2023, 123910D (16 March 2023); https://doi.org/10.1117/12.2661540

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