Determination of tiopronin content in drug by copper(I)-cuproine spectrophotometry

Xinrong Wen; Changqing Tu

doi:10.1117/12.2687453

28 August 2023 Determination of tiopronin content in drug by copper(I)-cuproine spectrophotometry

Xinrong Wen, Changqing Tu

Proceedings Volume 12724, Second International Conference on Biomedical and Intelligent Systems (IC-BIS 2023); 127240G (2023) https://doi.org/10.1117/12.2687453
Event: Second International Conference on Biomedical and Intelligent Systems (IC-BIS2023), 2023, Xiamen, China

Abstract

A method for the determination of tiopronin content in drug by copper(І)-cuproine spectrophotometry is established. The hydrosulfuryl(-SH) in tiopronin can quantitatively can reduce Cu2+ to Cu+, Cu+ react with cuproine to form copper(І)- cuproine amaranth complex in the condition of pH=5.0, the content of tiopronin can be determinated by measuring the absorbance of copper(І)-cuproine amaranth complex. The optimum conditions for the determination of tiopronin by copper(І)-cuproine spectrophotometry are discussed. Under the optimal conditions, the content of tiopronin in drug is determined, and the results are satisfactory.

Citation Download Citation

Xinrong Wen and Changqing Tu "Determination of tiopronin content in drug by copper(I)-cuproine spectrophotometry", Proc. SPIE 12724, Second International Conference on Biomedical and Intelligent Systems (IC-BIS 2023), 127240G (28 August 2023); https://doi.org/10.1117/12.2687453

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