Oxidative stress and male reproductive health

Kewen Yang

doi:10.1117/12.2692053

7 September 2023 Oxidative stress and male reproductive health

Kewen Yang

Proceedings Volume 12789, International Conference on Modern Medicine and Global Health (ICMMGH 2023); 127890F (2023) https://doi.org/10.1117/12.2692053
Event: International Conference on Modern Medicine and Global Health (ICMMGH 2023), 2023, Oxford, United Kingdom

Abstract

In addition to providing energy for the physiological activities of the human body, aerobic metabolism also produces reactive oxygen species (ROS), which have physiological functions such as transmitting information and have a certain negative impact on sperm. Although ROS is produced by mitochondria, it has still been identified as the main reason for the decline of sperm vitality. The possible mechanism is the destruction of sperm cell membrane, making it difficult for sperm to combine with oocyte. Therefore, some researchers began to focus on studying the impact of ROS on sperm activity and hope to find a treatment method for sexual incompleteness. So far, a large number of experiments have proved that ROS will cause bad effects such as sperm DNA. At the same time, ROS will oxidize polyunsaturated fatty acids (PUFA) in the cell membrane, resulting in damage to sperm cells and significantly decreased survivability. However, there are still some difficulties in the treatment of asthenospermia. This article mainly discusses the physiological function of ROS, the mechanism of suppressing sperm movement, the causes of ROS, related pathology in male reproductive systems, and health care and treatment methods in Chinese medicine and western medicine.

Citation Download Citation

Kewen Yang "Oxidative stress and male reproductive health", Proc. SPIE 12789, International Conference on Modern Medicine and Global Health (ICMMGH 2023), 127890F (7 September 2023); https://doi.org/10.1117/12.2692053

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